Abstract
Objectives: The saphenous vein is still one of the most commonly used grafts for coronary artery bypass grafting. Nevertheless several studies show an inferior long term patency compared to arterial grafts. This could be due to the histologic structure of the vein as it is not intended for a high pressure system. Another issue might be due to the intraoperative handling of the graft. It could be shown that by flushing the graft during harvesting and preparation accidential peak pressures over 600 mmHg occur inside the vessel. This might lead to endothelial damage of the graft and thus reduce quality and subsequently patency. Thus, controlling the flushing pressure could prevent endothelial damage. Therefore we investigated whether the usage of a pressure limited syringe influences graft quality and endothelial function.
Published Version
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