Presentations, etiology and outcome of patients with Chronic Renal Failure admitted at Urology Department, Mayo Hospital Lahore - A retrospective analysis of 1257 patients over a period of 10 years.

Abstract

Chronic kidney failure is a common and serious medical problem. It is characterized by progressive destruction of renal mass with irreversible sclerosis and loss of nephrons. End-stage renal (kidney) disease is the point in this progression when the kidneys no longer function well enough to support life. The objective of this retrospective study is to analyze different patrons of chronic renal failure its etiology and outcome. Over a period of ten years starting from January 1992 a total of 1257 patients presents with the diagnosis of chronic renal failure to the NephroUrology Department of Mayo Hospital Lahore. The minimum age at presentation was 2.5 years and maximum age was 66 years with mean age of 37.8 years. Malaise, loss of energy, nausea, vomiting and symptoms of anemia were the major presentation in all the patients. Uncontrolled Diabetes Mellitus was seemed to be the major cause of chronic renal failure which was diagnosed in 441 patients, followed by uncontrolled hypertension in 253 patients, polycystic kidney disease in 107 patients, Glomerulonephritis in 97 patients, reflux nephropathy in 96 patients, obstructive (stones) nephropathy in 78 patients, drugs/nephrotoxic agents 39 patients, congenital renal obstructions 21 patients and hypoplastic kidney in 03 patients. 339 (27%) patients were primarily put on to conservative treatment. In 568 (45%) patients haemodialysis was started and in 350 (28%) patients peritoneal dialysis was started. 8.51% (n=l08) patients under went renal transplantation.