Abstract
N-alkylation of chitosan was performed in a mixture of methanol and 1% acetic acid containing different amounts of monosaccharides or disaccharides including glucose, galactose, glucosamine, fructose, lactose, maltose and cellobiose. All the N-alkylated chitosan derivatives with monosaccharides were insoluble in aqueous solution (pH 7), while N-alkylated chitosan derivatives with disaccharides were easily soluble in distilled water, and the N-alkylated chitosan derivatives with lactose were soluble only at high pH. The degree of substitution (DS) of the N-alkylated chitosan derivatives increased with increasing disaccharides levels and with increasing reaction time. The reduced viscosity of the N-alkylated chitosan derivatives with disaccharides decreased with increasing DS. Apparent viscosity and pseudoplasticity of the N-alkylated disaccharide containing derivative solutions generally decreased with increasing DS. Although apparent viscosities of N-alkylated chitosan derivatives with low DS decreased with increase in pH or ionic strength, changes in high DS N-alkylated chitosan derivatives with pH values or ionic strength were not marked.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.