Abstract

Curcumin derivative-functionalized graphene oxide (CUDE-f-GO) composite was synthesized via direct polycondensation reaction in a binary phase system. The composite was characterized by FTIR, 1H NMR, Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), thermal gravimetric analysis (TGA) and atomic force microscopy (AFM). Digital camera and transmission electron microscopy (TEM) images showed that the composite had better dispersion in phosphate buffer solution (PBS) than graphene oxide (GO). The photophysical experiments revealed that the photoluminescence (PL) properties were significantly enhanced when curcumin derivative (CUDE) was covalently grafted on the surfaces of GO. The in vitro and in vivo bioimaging results showed that CUDE-f-GO composite was an ideal optical material for biological imaging because of its good photostability, low cytotoxicity, bright bioimaging and excellent tumor targeting ability.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call