Abstract
In this study, a magnetic molecularly imprinted polymer (MMIP) with a well-defined core-shell nanostructure for extracting fluoroquinolones (FQs) using heptakis (β-cyclodextrin-ionic liquid) (ILs(2)-βCD), ofloxacin (OFL), triallyl cyanate (TAC), and azobisisobutyronitrile as the functional monomer, template molecule, crosslinking agent, and initiator, respectively, has been directly fabricated in water-containing systems. The morphology, structure, and magnetic properties of the MMIP were characterized using transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and vibrating sample magnetometry (VSM). Recombination experiments and competitive adsorption experiments showed that the imprinted material, MMIP, has a good binding capacity (35.85 mg/g), special selectivity, and excellent ability to eliminate matrix interference. Its molecular recognition mechanisms were investigated by the experimental validation with ultra-violet spectroscopy (UV) and proton nuclear magnetic resonance (1HNMR), which inferred that hydrophobic and electrostatic interactions are the driving forces for the selective recognition of MMIP. By coupling the MMIP adsorbent with high-performance liquid chromatography, an approach was established to enhance the selective recognition of four structurally similar FQ compounds in real water samples. Several main factors affecting extraction efficiency, such as the sample solution pH value, MMIP dosage, and elution solvent type, were preliminarily optimized. Under the optimal conditions, the method has a good linear relationship (R2 greater than 0.9990) over a wide range (0.5–1000 μg/L). The recoveries of the four FQs ranged from 80.11% to 106.71%, and the limits of detection were between 0.43 and 1.83 μg/L. The results show that this water-compatible molecularly imprinted polymer has broad application prospects for efficient identification and separation as well as enrichment of trace FQs in complex matrices.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
