Preparation of poly (KH570-co-DVB) microspheres and application in HPLC for separation of benzene and benzene homologs

Abstract

High-performance liquid chromatography (HPLC) is one of the most widely used separations and analysis methods, which has become an indispensable part of the separation and detection of mixtures, qualitative and quantitative analysis and other scientific research and social production fields. Because of the decisive effect of the chromatographic column on analysis and separation, it has become the core of research in the chromatographic system. In the past decades, the research and development of new chromatographic column stationary phase have been highly concerned. Monodisperse polymer microsphere, because of its special large pore structure, has good permeability and high specific surface area, which can be used as special materials in various fields, such as adsorption materials in the separation process, HPLC column packing, catalyst carrier, preparation template of nanomaterials and nuclear fusion targeting materials. When it is used in HPLC, because of the good permeability of microspheres, it can effectively improve the separation efficiency and performance. In this article, based on the previous work, a number of new polymer microspheres were prepared, and the prepared microspheres were used for the separation and detection of HPLC, and their physical and chemical properties were studied.