Year-end Sale % OFF 
Abstract
We developed a templating method based on NeutrAvidin–biotin interaction, for the preparation of hollow microcapsules composed of DNA. In this method, porous calcium carbonate microparticles were employed as a sacrificial template and an adsorbent for DNA, and NeutrAvidin was chosen as a cross-linker for biotin-labeled DNA. By using biotin-labeled DNA with a degree of biotinylation high enough to retain a hollow spherical structure, hollow DNA microcapsules were obtained with the same size as the templates after the dissolution of the templates with chelating agents. In addition, the combination biotin-labeled DNA and NeutrAvidin could be applied to layer-by-layer assembled multilayers. Layer-by-layer assembled capsules exhibited the size-dependent permeability of macromolecular solutes. This study suggests that our method would be facile and widely applicable to prepare various polymer capsules.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Colloids and Surfaces A: Physicochemical and Engineering Aspects
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
