Year-end Sale % OFF 
Abstract
To prepare hollow microcapsules composed of native DNA, we developed a templating method using porous calcium carbonate microparticles as sacrificial templates. At first, DNA was adsorbed onto calcium carbonate microparticles, and then the adsorbed DNA was covalently cross-linked with each other by using ethylene glycol diglycidyl ether. After the dissolution of the templates, the resultant DNA capsules ranged from 1.5 to 8 μm in diameter, according to ionic strength. The low cross-linked and highly cross-linked DNA capsules exhibited enzymatic degradability and permeability that was dependent on the molecular weight of macromolecular solutes, respectively. This method has the potential to be used for the preparation of various single-component polymer capsules.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Colloids and Surfaces A: Physicochemical and Engineering Aspects
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
