Abstract

Objective To prepare biomimetic,intelligent scaffold for tissue engineering of thumb distal phalanx using gathered three-dimensional (3D) data. Methods Distal phalanxes from fresh adult cadaver thumbs were subject to micro -CT scanning.The DICOM data from micro-CT scans were processed using Mimics software to form the macro and micro biomimetic 3D printing STL file.3D printer was then used to prim out a scaffold of a phalanx. Results The data acquired by micro-CT scanning can be rapidly prototyped after being edited with Mimics and directly used by 3D printing system to construet a biomimetic,intelligent scaffold.Conclusion Biomimetic,intelligent scaffold based on micro-CT and 3D printing has clinical significance in reconstruction of destructed thumbs. Key words: Tissue engineering; Finger phalanges; Micro-CT

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