Abstract
Schiff base derived from 2-aminophenol and 3-formyl-2-hydroxy-6-methoxyquinoline and its Mn(II) and Fe(II) complexes were synthesized and characterized by melting point and decomposition temperature, elemental analysis, molar conductivity, infrared (IR) spectral analysis, atomic absorption spectroscopy (AAS) analysis, solubility test, and magnetic susceptibility. The Fourier-transform infrared spectroscopy (FTIR) spectral data of the Schiff base determined showed a band at 1622 cm−1 and this was assigned to the v (C=N), which is a feature of azomethine group. The same band was observed to shift to lower frequencies 1577 and 1599 cm−1 in the complexes suggesting coordination of the Schiff base with the respective metal(II) ions. Molar conductance values 14.58 and 12.65 Ω−1∙cm2∙mol−1 show that the metal complexes were non-electrolyte in nature. The magnetic susceptibility of the complexes was determined and the gram magnetic susceptibility of the complexes was found to be positive, revealing that they are paramagnetic. The elemental analysis of the complexes for C, N and H determined suggested 1:1 metal to ligand ratio. The result of the antimicrobial studies showed that, the metal(II) complexes exhibited better antibacterial and antifungal activity than the Schiff base.
Highlights
Schiff base is a compound containing an imine or azomithine group, (-N=CH-)
The Fourier-transform infrared spectroscopy (FTIR) spectral data of the Schiff base determined showed a band at 1622 cm−1 and this was assigned to the v (C=N), which is a feature of azomethine group
The Schiff base and its metal(II) complexes were prepared in good yield, the physical properties of the synthesized ligand and its complexes were analyzed and presented in (Table 1)
Summary
Schiff base is a compound containing an imine or azomithine group, (-N=CH-). It is a condensation product of aldehyde or ketone with primary amine and was first reported in 1864 by a German chemist Hugo Schiff [1]. Azomithune nitrogen in the Schiff base, is of considerable chemical and biological importance, and provides binding sites for metal ions and makes attachments with various substrate of bio-molecules like proteins and amino acids in biological systems and that of diseases-causing germs [3]. These compounds play an important role in medicinal fields because of their wide spectrum of biological activities. Many of them have antimicrobial and anticancer effect as biologically important compounds [4]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
