Abstract

Objective: To prepare Chitosan-Multi Walled Carbon Nanotube (Ch: MWCNT) nanocomposite with different chitosan: MWCNT ratios were successfully prepared by modifying chitosan and functionalized MWCNT. Methods: The prepared Ch-MWCNTs nanocomposite was characterized by TEM analysis confirming the MWCNTs homogenously distributed in chitosan matrix. Furthermore, TEM results indicate the resulting MWCNT tubular length morphology. Based on the FTIR results which confirm the presence of the C = C. The FTIR indicates that the characteristic functional groups of MWCNTs and chitosan are successfully present in modified nanocomposite. Findings/Application: Nanocomposite Ch/MWCNT showed higher antimicrobial activity against both Gram negative and Gram positive bacteria. The nanocomposites are highly differentiable at the lower conc. as even only 1% conc. from multifunctional nanocomposite has found to be very effective against the target microorganisms. Minimal Inhibitory Concentrations (MIC) of Ch-MWCNT (100:50 Ch/MWCNT) against Gram negative and Gram positive pathogenic bacteria between 0.5 and 0.0625 μl, and the growth inhibition effect has been observed in a concentration-dependent species. Keywords: Antimicrobial, Chitosan, CNT, Nanocomposites

Highlights

  • Since their discovery in by[1], the CNTs have received much attention in many scientific fields

  • It is clear that, there is a noticeable homogeneity between the modified MWCNT and chitosan and the modified MWCNT has a good distribution over the chitosan polymer surface where the homogeneity increased by increasing the percentage of CNT and

  • The antibacterial activities of Ch, MWCNT and Ch-MWCNT nanocomposite were tested against four bacterial spp. by disc diffusion method and the results are shown in Table 1 and Figures 3 and 4

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Summary

Introduction

Since their discovery in by[1], the CNTs have received much attention in many scientific fields. The remarkable electronic properties of CNTs, their sensitivity to the external environment and their nanoscale dimension, make them very attractive compounds for biosensors for the detection of biomolecules. The biosensors based on CNTs developed so far can detect proteins, glucose, DNA and urea[2,3,4]. Research is still underway to solve the problem of CNT dispersion in both organic solvents and polymer matrices. Their covalent and non-covalent functionalization, using new alternatives, may be the most appropriate solution to broaden their application. The use of a natural polymer has been favored, because of its natural biocompatibility and for ecological reasons

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