Preparation and performance analysis of zinc-iron-based nanomaterials for targeted transport

Abstract

Background Nanomaterials have applications in traditional Chinese medicine in the fields of medical equipment manufacturing, targeted transportation, and drug synergistic therapy. Objective The research aims to discuss the performance and performance of zinc-iron-based nanomaterials in medical drug delivery and synergistic drug therapy. Methods Using Prussian materials as precursors, magnetic zinc-iron nanomaterials were prepared by ZnCl2 and K3[Fe (CN)6]. Moreover, the morphology and composition of the material were analyzed. Results X-ray analysis was conducted on the prepared Zn3[Fe (CN)6]2·xH2O nanomaterials, and their purity met the design requirements. At the same time, drug loading analysis was conducted on Zn3[Fe(CN)6]2·xH2O, and the release of capsaicin reached 86.3% under a certain phosphate buffer solution. Meanwhile, Zn3[Fe (CN)6]2·xH2O loaded tetracycline could release up to 90% in phosphate buffer solution. Antibacterial tests were conducted on self-made Zn3[Fe(CN)6]2·xH2O samples and ZnFe2O4/ZnO. The Zn3[Fe(CN)6]2·xH2O samples showed a more significant inhibitory effect on cancer cells after loading with capsaicin. Conclusion The zinc-iron-based nanomaterials prepared by the research have excellent performance in drug loading and safety, indicating their significant potential for development in the medical field.