Abstract
This study aimed to prepare and evaluate sustained release microspheres for the treatment of diabetic neuropathy using Various polymers including sodium alginate, ethyl cellulose, HPMC K100, Carbopol 934, and Eudragit L-100-55. Polymers were employed to assess their impact on several crucial parameter’s entrapment efficiency, production yield Particle size analysis, swelling index, in vitro dissolution, and release kinetics. The production yield of microspheres varied depending on the polymer used, with some polymers performing in advanced yields. Entrapment effectiveness was set up to be optimal with certain polymer combinations. Particle size analysis indicated that the microspheres were within the asked range for controlled release operations. The swelling index showed polymer-dependent lump actions. In vitro dissolution studies demonstrated sustained medicine release over time, with different polymers impacting both the release rate and profile. medicine release kinetics analysis revealed that the release followed specific models, reflecting the commerce between the microsphere matrix and the medicine.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
