Abstract
Pioglitazone is an oral hypoglycemic drug, used for the treatment of type 2 diabetes. The main objectives of this study were to improve aqueous solubility of Pioglitazone by preparing its solid dispersion by fusion method using various carriers that will improve its absorption and subsequent bioavailability. The prepared tablets (TF1-TF5) were evaluated for various parameters i.e.shape and size, weight variation, hardness, friability, disintegration time, drug content etc. The prepared tablet passed all the tests.Finally, it can be concluded that solid dispersion of Pioglitazone may be prepared to improve its solubility and dissolution. This will lead to better absorption and hence improved bioavailability of the drug (Pioglitazone).
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
