Preparation and Characterization of Novel Mixed Periodic Mesoporous Organosilica Nanoparticles.

Hao Li,Clarence Charnay,Laurence Raehm,Jean-Olivier Durand,Roser Pleixats

doi:10.3390/ma13071569

Abstract

We report herein the preparation of mixed periodic mesoporous organosilica nanoparticles (E-Pn 75/25 and 90/10 PMO NPs) by sol-gel co-condensation of E-1,2-bis(triethoxysilyl)ethylene ((E)-BTSE or E) with previously synthesized disilylated tert-butyl 3,5-dialkoxybenzoates bearing either sulfide (precursor P1) or carbamate (precursor P2) functionalities in the linker. The syntheses were performed with cetyltrimethylammonium bromide (CTAB) as template in the presence of sodium hydroxide in water at 80 °C. The nanomaterials have been characterized by Transmission Electron Microscopy (TEM), nitrogen-sorption measurements (BET), Dynamic Light Scattering (DLS), zeta-potential, Thermogravimetric Analysis (TGA), FTIR, 13C CP MAS NMR and small angle X-ray diffraction (p-XRD). All the nanomaterials were obtained as mesoporous rodlike-shape nanoparticles. Remarkably, E-Pn 90/10 PMO NPs presented high specific surface areas ranging from 700 to 970 m2g−1, comparable or even higher than pure E PMO nanorods. Moreover, XRD analyses showed an organized porosity for E-P1 90/10 PMO NPs typical for a hexagonal 2D symmetry. The other materials showed a worm-like mesoporosity.

Highlights

Periodic mesoporous organosilica materials, at the bulk (PMO) [1,2,3] and nanoscale (PMONPs) level, are fundamentally unique because they have several advantages, such as robust porous organic-inorganic framework [4], porous channels [5], tunable pore size organization [6,7], biocompatibility [8], and the highest organic contentmaterials [9].the functionalization of the inner and outer surface allows the modulation of the properties and enable dispersibility in aqueous or organic solvents [10]
We describe the preparation and full characterization of novel mixed PMO NPs which have been obtained by sol-gel co-condensation of E-1,2-bis(triethoxysilyl)ethylene (BTSE or E) [38]
The synthesis of P1 is depicted in Scheme 1

Summary

Introduction

At the bulk (PMO) [1,2,3] and nanoscale (PMONPs) level, are fundamentally unique because they have several advantages, such as robust porous organic-inorganic framework [4], porous channels [5], tunable pore size organization [6,7], biocompatibility [8], and the highest organic content (nano)materials [9].the functionalization of the inner and outer surface allows the modulation of the properties and enable dispersibility in aqueous or organic solvents [10]. NPs) level, are fundamentally unique because they have several advantages, such as robust porous organic-inorganic framework [4], porous channels [5], tunable pore size organization [6,7], biocompatibility [8], and the highest organic content (nano)materials [9]. The PMO (and PMO NPs) can be degraded when specific functional groups sensitive to redox, acid-base, biochemical, or photochemical reactions are present in the structure of the organic framework [13,14,15]. In nanomedicine, properties of PMO NPs such as low hemolytic behavior [18], increased biocompatibility, higher loading capacities, physico-chemical adjustability of the pores [19] and designed biodegradability [20], are important when compared to mesoporous silica nanoparticles

Methods

Results

Conclusion