Preparation and characterization of caprine bone derived mineral substituted hydroxyapatite/phyllanthus acidus extract for biomedical applications

Abstract

Natural (Caprine bone) Hydroxyapatite/Phyllanthus acidus and Gallium substituted Hydroxyapatite/Phyllanthus acidus composite powders were successfully synthesized by thermal decomposition method. The synthesized powders were confirmed function group by FTIR and the phase purity, crystalline size through XRD results. The SEM results show that the size of the Hydroxyapatite powders reduced with the substitution of Gallium in the natural Hydroxyapatite composite which leads to the formation of finer powders and uniform surface morphology. Natural Gallium substituted Hydroxyapatite/Phyllanthus acidus composite were successfully achieved to obtained better morphology. Gallium substituted Hydroxyapatite/Phyllanthus acidus shows better antibacterial activity compare to Hydroxyapatite/Phyllanthus acidus composite.