Abstract
This work produced new homogenous and heterogeneous polymers with medical qualities to expand the controlled drug, as well as new drug-substituted monomers. The following three lines were included in this work: Preparation is the first stage (compound1) via reaction of furan-2,5-dione with 4-aminobenzoic acid, then compound (1) was reacted with amino drug such as (mesalazine) compound(2) monomer. Second line: The homogeneous polymer (compound 3) was produced by employing MEKP as an initiator in the polymerase reaction of the monomer's (compound 2) free radicals under nitrogen. Third line: Using MEKP as an initiator, The Polymerase Reaction of The Free Radicals of the monomer (compound2) with the acrylic acid under nitrogen was used to introduce the heterogeneous polymer (compound 3).Compound 2's monomer is described using FT-IR. Studies were conducted on the characteristics of biological activity. It was determined whether medication loading (compounds 3 and 4) had an anti-proliferating impact on the colon cancer cell lines. Compounds 3 and 4 may be a suitable and promising approach for creating an efficient drug delivery system for therapeutic use against colon malignancies, according to cytotoxicity assessments.
Published Version
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