PREPARATION AND ANTI-MICROBIAL STUDY OF KASASHWASAVIDHUNANO RASA IN-VITRO

Abstract

Kasashwasavidhunano Rasa is a drug used in Respiratory disorders in the Indian System of Medicine. It is an herbomineral formulation made up of Parad, gandhak, yavakshara, ruchaka lavana, and maricha churna by triturating in Tulsi patra Swarasa and indicated in Shwasa, Kasa. This action of Kasashwasavidhunano Rasa may be due to its antimicrobial activity so the in vitro antimicrobial activity was assessed by the Agar Disc Diffusion method concerning streptococcus pneumonia and Morxella catarrhal. Objective: To prepare and evaluate the antimicrobial effect of Kasashwasavidhunano Rasa. Method: Kasashwasavidhunano Ras was prepared using the reference of Yogratnakar. Parada (Mercury) and Gandhak (sulfur) were purified and then triturated to form Kajjali. Then raw drugs of maricha were converted into powder form, and all the ingredients i.e. kajjali, maricha churna, yavakshar, ruchaka lavana were mixed and triturated with the help of Tulsi swaras. The final product was in churna from which it was dried and stored. The antimicrobial activity of Kasashwasavidhunano Ras against streptococcus pneumonia and morxella catarrhal bacteria was evaluated using the agar cup diffusion method. Result: Kasashwasavidhunano Ras shows a significant antibacterial spectrum against streptococcus pneumonia and morxella catarrhal. Conclusion: This study shows that Kasashwasavidhunano Ras has antimicrobial potency and it can be clinically used for infectious respiratory disorders.