Abstract

Introduction: PCOS syndrome is a common endocrine disease in females. Previous studies have stated that PCOS is associated with an increased risk of endometrial hyperplasia and cancer. This study aims to investigate the feasibility of using the HOPE system in KHUH for exploring the association between PCOS and Endometrial hyperplasia and cancer. Methods: A retrospective cross-sectional study to find the incidence of association between PCOS and Endometrial cancer cases following up in King Hamad University Hospital (KHUH) and Bahrain Oncology Center (BOC) in 2018. Results: A total of 241 women included in our study. A total of 165 women were diagnosed with PCOS in 2018, and a total of 55 women that underwent endometrial sampling, and 21 women diagnosed with endometrial cancer. No significant relationship between PCOS and EH and EC. High BMI was found significant in all sample groups. Conclusion: Our study showed that there is a link between PCOS and EC but the percentages are very low. A large prospective study with a control group would provide further information regarding the relationship between PCOS and EC.

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