Abstract
Preliminary Phytochemical Analysis and Invitro Antiviral Activity of Ethanolic extract of Whole plant of Tinospora cordifolia (Thunb.) Miers against Hepatitis-A Virus
Highlights
Over the centuries humans have relied on plants for basic needs
An herb is a plant or plant part used for its scent, flavor, and/or therapeutic properties Herbal product design refers to the process of developing, standardizing, processing, and validating an herbal product for the market [2]
The results clearly indicated the selected plant extract shows a dose dependent activity and it was maximum at 50 μg/mL concentration where it shows only 56.24% of virus viability and it was comparable to standard drug where it shows 43.01% of viability
Summary
Over the centuries humans have relied on plants for basic needs. It was estimated in the Bulletin of the World Health Organization (WHO) that around 80 % of the world’s population relied on medicinal plants as their primary healthcare source [1]. Tinospora cordifolia (Thunb.) Miers, (Figure 1) which is known by the common names heart-leaved moonseed, guduchi and giloy, is an herbaceous vine of the family Menispermaceae indigenous to the tropical areas of India, Myanmar and Sri Lanka [4]. It grows throughout tropical India, ascending to an altitude of 300m. The present work highlighted the invitro anti–viral activity of ethanolic extract of whole plant of Tinospora cordifolia (Thunb.) Miers against HAV through MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) cell proliferation assay using Huh-7 cell lines
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