Abstract
Several types of centrifugal blood pump have been developed for artificial heart from its beneficial aspects compared with other types of blood pump. The designs of impeller and volute casing in a centrifugal blood pump are important factors affecting on its hydraulic performances. For initial evaluation of the impeller and the volute casing designed by 3-Dimensional modeling and Computational Fluidics Dynamics for its optimization, the animal experiments were conducted in comparison with Biopump™ (Medtronic BioMedicals, USA) as control group. Extracorporeal circulations with total cardiopulmonary bypass in swines (BW: 28.2±2.9 kg) were maintained for 2 hours at the flow rate of 1.5∼2 L/min in both groups. Hemodynamic and laboratory parameters, and pump performance parameters were measured during the experiments. The pressure differences between inlet and outlet in the study group were measured as 90–110 mmHg lower than that of control group as 150-200mmHg. But the higher motor speeds of 4700 rpm were required for maintaining the flow rate of 2 L/min than 2200 rpm in the control group. The plasma free hemoglobin data were higher than that of control group, possibly due to the impellar design or high motor speeds. More improvements including appropriate materials selection need to be done. This preliminary study shows the possibility of a centrifugal pump with optimized design of impeller and volute casing as a good candidate of artificial heart pumps in near future.
Published Version
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