Pregnancy-Related-Acute Kidney Injury in Jigawa, Nigeria

Abstract

Introduction: Pregnancy-related acute kidney injury (PR-AKI) is a significant cause of maternal morbidity and mortality. Objective: This study aimed to determine the causes and outcomes of PR-AKI management. Methods: This was a two-year retrospective review of patients managed for PR-AKI between 1 October 2021 and 31 September 2023 in the Department of Obstetrics and Gynaecology of Rasheed Shekoni Federal University Teaching Hospital Dutse. Patients’ data were obtained from their case files. Results: One hundred and three women were diagnosed with PR-AKI out of 1,647 admissions during the review period. The mean age of the patients was 27 7.5 years, with an age range of 15 to 48 years. The mean parity was 4.513.2 and most (47.6%) patients were grand-multipara. The majority (70.7%) booked for antenatal care in primary healthcare centres, and only 2(3.1%) booked in tertiary hospitals. The commonest cause of PRAKI was obstetric haemorrhage (48.5%), with postpartum haemorrhage and antepartum haemorrhage accounting for 72% and 28%, respectively. Seventy-five (72.8%) patients received a blood transfusion, while 28 (27.2%) had haemodialysis. Thirty-five (33.9%) deaths were recorded. Conclusion: This study revealed that PRAKI was common, and obstetric haemorrhage, hypertensive disorders and sepsis were the leading causes.