Pregnancies after Transfer of Vitrified Biopsied Blastocysts

Abstract

Objective To show two cases describing the successful pregnancies after transplantation of vitrified biopsied embryos after preimplantation genetic diagnosis (PGD). Methods PGD by day 3 embryo biopsy was performed. Excess embryos were frozen using vitrification method. Four months later, the patient elected to undergo a frozen-thawed embryo transfer (FET) cycle. Results These two patients became pregnant and both of them delivered healthy PGD baby respectively. Conclusion This report shows that vitrification is an efficient and practical method for embryo cryopreservation during PGD. Frozen-thawed blastocysts that do survive obtained from vitrified D3 biopsied embryos are able to implant.