Abstract

BackgroundIncreased hospital length of stay is an important cost driver in hospitalized low-risk pulmonary embolism (LRPE) patients, who benefit from abbreviated hospital stays. We sought to measure length-of-stay-associated predictors among Veterans Health Administration LRPE patients.MethodsAdult patients (aged ≥18 years) with ≥1 inpatient pulmonary embolism (PE) diagnosis (index date = discharge date) between 10/2011–06/2015 and continuous enrollment for ≥12 months pre- and 3 months post-index were included. PE patients with simplified Pulmonary Embolism Stratification Index score 0 were considered low risk; all others were considered high risk. LRPE patients were further stratified into short (≤2 days) and long length of stay cohorts. Logistic regression was used to identify predictors of length of stay among low-risk patients.ResultsAmong 6746 patients, 1918 were low-risk (28.4%), of which 688 (35.9%) had short and 1230 (64.1%) had long length of stay. LRPE patients with computed tomography angiography (Odds ratio [OR]: 4.8, 95% Confidence interval [CI]: 3.82–5.97), lung ventilation/perfusion scan (OR: 3.8, 95% CI: 1.86–7.76), or venous Doppler ultrasound (OR: 1.4, 95% CI: 1.08–1.86) at baseline had an increased probability of short length of stay. Those with troponin I (OR: 0.7, 95% CI: 0.54–0.86) or natriuretic peptide testing (OR: 0.7, 95% CI: 0.57–0.90), or more comorbidities at baseline, were less likely to have short length of stay.ConclusionUnderstanding the predictors of length of stay can help providers deliver efficient treatment and improve patient outcomes which potentially reduces the length of stay, thereby reducing the overall burden in LRPE patients.

Highlights

  • Increased hospital length of stay is an important cost driver in hospitalized low-risk pulmonary embolism (LRPE) patients, who benefit from abbreviated hospital stays

  • LRPE patients with a long length of stay (LOS) were older (60.7 vs 58.4 years, mean difference: 2.3, 95% confidence intervals (CIs): 1.28-3.37) and more likely to be male (94.6% vs 91.3%, relative risk: 1.04, 95% CI: 1.01-1.06) as compared to LRPE patients with a short LOS

  • The long LOS cohort had a higher proportion of patients with troponin I testing (38.1% vs 30.1%, relative risk: 1.3, 95% CI: 1.11-1.45) during index hospitalization as compared to the short LOS cohort (Table 1)

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Summary

Introduction

Increased hospital length of stay is an important cost driver in hospitalized low-risk pulmonary embolism (LRPE) patients, who benefit from abbreviated hospital stays. LRPE patients with computed tomography angiography (Odds ratio [OR]: 4.8, 95% Confidence interval [CI]: 3.82-5.97), lung ventilation/perfusion scan (OR: 3.8, 95% CI: 1.86-7.76), or venous Doppler ultrasound (OR: 1.4, 95% CI: 1.08-1.86) at baseline had an increased probability of short length of stay. Those with troponin I (OR: 0.7, 95% CI: 0.54-0.86) or natriuretic peptide testing (OR: 0.7, 95% CI: 0.57-0.90), or more comorbidities at baseline, were less likely to have short length of stay. Low-risk PE (LRPE) patients may be treated safely in an outpatient setting obviating a hospital stay.[5]

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