Abstract
Background. The frequency of erectile dysfunction (ED) complicating diabetes mellitus (DM) is reportedly high. However, its risk factors have not been well studied. Methods. This was a cross-sectional study of 160 male type 2 DM adults, aged 30–70 years, attending a tertiary healthcare clinic. Demographic and relevant clinical information was documented. Erectile function was assessed using an abridged version of the International Index of Erectile Function (IIEF-5). All subjects were evaluated for central obesity, glycemic control, peripheral arterial disease (PAD), autonomic neuropathy, dyslipidemia, and testosterone deficiency. Results. 152 (95%) patients with a mean age of 60.3 ± 8.8 years completed the study. 71.1% had varying degrees of ED, while 58.3% suffered from a moderate-to-severe form. Independent predictors of ED [presented as adjusted odds ratio (95% confidence interval)] were longer duration of DM, 1.14 (1.02–1.28), PAD, 3.87 (1.28–11.67), autonomic neuropathy, 3.51 (1.82–6.79), poor glycemic control, 7.12 (2.49–20.37), and testosterone deficiency, 6.63 (2.61–16.83). Conclusion. The prevalence of ED and its severe forms was high in this patient population. Poor glycemic control and testosterone deficiency were the strongest risk factors for ED, making it possibly a preventable condition.
Highlights
Diabetes mellitus (DM) is a chronic metabolic disorder associated with significant morbidity and mortality
Definite, and severe autonomic neuropathy was observed in 27.6%, 13.2%, and 10.5%, respectively, while 37.5% had low testosterone concentration,
Such facility is lacking in our centre. This area needs to be explored by other researchers in this subject. In this small population of men with type 2 diabetes, a high frequency of erectile dysfunction was observed and this was of moderate-to-severe intensity in over half of those affected
Summary
Diabetes mellitus (DM) is a chronic metabolic disorder associated with significant morbidity and mortality. Erectile dysfunction is associated with grave psychosocial and clinical consequences including depression and poor quality of life [5]. Despite the aforementioned clinical importance of ED in diabetic men, studies have shown that most clinicians do not enquire about sexual dysfunction during consultations and the prevalence. The frequency of erectile dysfunction (ED) complicating diabetes mellitus (DM) is reportedly high. This was a cross-sectional study of 160 male type 2 DM adults, aged 30–70 years, attending a tertiary healthcare clinic. Independent predictors of ED [presented as adjusted odds ratio (95% confidence interval)] were longer duration of DM, 1.14 (1.02–1.28), PAD, 3.87 (1.28–11.67), autonomic neuropathy, 3.51 (1.82–6.79), poor glycemic control, 7.12 (2.49–20.37), and testosterone deficiency, 6.63 (2.61–16.83). Poor glycemic control and testosterone deficiency were the strongest risk factors for ED, making it possibly a preventable condition
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