Abstract
There are many clinical scoring criteria for predicting the risk of death in patients with acute ST-segment elevation myocardial infarction (STEMI), but most of the indicators are complex to calculate and are not suitable for use in primary hospitals. Neutrophil to lymphocyte ratio (NLR) and red cell distribution width (RDW) are blood routine indicators that are easy to obtain and may help primary hospitals to evaluate the risk of death in patients with STEMI. Our aim was to explore the predictive value of NLR combined with RDW in the long-term prognosis of patients with STEMI after emergency percutaneous coronary intervention (PCI). A total of 181 patients with STEMI who underwent emergency PCI in the Affiliated Hospital of Pu-tian University from January 2017 to August 2018 were selected. Clinical profile, prognosis of all patients were collected. P value < 0.05 was considered significant. In all patients, cardiovascular death during the follow-up period was defined as cardiovascular death group, and surviving during the follow-up period was defined as survival group. There were no significant differences in demography and comorbidities between the two groups. The differences between the two groups in NLR, RDW, C-reactive protein, N-terminal-pro B type natriuretic peptide were statistically significant (P < 0.01). Binary logistic regression analysis showed that NLR (OR = 1.122, 95% CI 1.041 ~ 1.210, P = 0.003) and RDW (OR = 1.288, 95% CI 1.126 ~ 1.472, P = 0.0005) were important predictors of mortality in patients with STEMI (P < 0.05). Kaplan–Meier analysis showed that as the NLR increased, the risk of death increased (P < 0.001). In conclusion, NLR and RDW are independent predictors of cardiovascular death in patients with STEMI, and they have a certain predictive value.
Highlights
segment elevation myocardial infarction (STEMI) refers to acute myocardial ischemic necrosis, which can lead to acute inflammation and stress response characterized by increased leukocyte mobilization in the area of myocardial n ecrosis[2]
Based on the analysis of the results of 2-year follow-up of STEMI patients with percutaneous coronary intervention (PCI), this study discussed the predictive value of neutrophil-to-lymphocyte ratio (NLR) and Red cell distribution width (RDW) in the long-term prognosis of these patients, in order to establish a simple, non-invasive, cost-effective method to evaluate the prognosis and inform clinical decision making
The diagnosis of acute ST segment elevation myocardial infarction is in accordance with the guidelines for diagnosis and treatment of acute ST segment elevation myocardial infarction published by Chinese Medical Association in 2 01514
Summary
STEMI refers to acute myocardial ischemic necrosis, which can lead to acute inflammation and stress response characterized by increased leukocyte mobilization in the area of myocardial n ecrosis[2]. White blood cell count within 24 h after admission is an independent predictor of death and major adverse events in patients with acute myocardial infarction[3], and low levels of lymphocytes are significantly associated with cardiovascular disease mortality[4]. Predict the long-term mortality of patients with acute ST-segment elevation myocardial infarction[7], and reflect the severity of coronary artery disease, and is related to the SYNTAX score and Gensini s core[8]. Based on the analysis of the results of 2-year follow-up of STEMI patients with percutaneous coronary intervention (PCI), this study discussed the predictive value of NLR and RDW in the long-term prognosis of these patients, in order to establish a simple, non-invasive, cost-effective method to evaluate the prognosis and inform clinical decision making
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
