Abstract

ABSTRACTObjective:To evaluate the length hospital stay and predictors of prolonged hospitalization after RRP performed in a high-surgical volume teaching institution, and analyze the rate of unplanned visits to the office, emergency care, hospital readmissions and perioperative complications rates.Materials and Methods:Retrospective analysis of prospectively collected data in a standardized database for patients with localized prostate cancer undergoing RRP in our institution between January/2010 - January/2012.A logistic regression model including preoperative variables was initially built in order to determine the factors that predict prolonged hospital stay before the surgical procedure; subsequently, a second model including both pre and intraoperative variables was analyzed.Results:1011 patients underwent RRP at our institution were evaluated. The median hospital stay was 2 days, and 217 (21.5%) patients had prolonged hospitalization. Predictors of prolonged hospital stay among the preoperative variables were ICC (OR. 1.40 p=0.003), age (OR 1.050 p<0.001), ASA score of 3 (OR. 3.260 p<0.001), prostate volume on USG-TR (OR, 1.005 p=0.038) and African-American race (OR 2.235 p=0.004); among intra and postoperative factors, operative time (OR 1.007 p=0.022) and the presence of any complications (OR 2.013 p=0.009) or major complications (OR 2.357 p=0.01) were also correlated independently with prolonged hospital stay. The complication rate was 14.5%.Conclusions:The independent predictors of prolonged hospitalization among preoperative variables were CCI, age, ASA score of 3, prostate volume on USG-TR and African-American race; amongst intra and postoperative factors, operative time, presence of any complications and major complications were correlated independently with prolonged hospital stay.

Highlights

  • The number of new cases of prostate cancer worldwide is higher than 1.1 million each year, which represents 15.3% of all incident cancer cases in developed countries and 4.3% of the cases in developing countries [1]

  • With improvements in the anesthetic technique and intra-operative care, the mean hospitalization time has decreased [6,7,8]; subsequently, this time was further reduced by the establishment of optimized strategies for perioperative care after retropubic radical prostatectomy (RRP), which resulted in short hospitalization, without an associated increase in the postoperative complication rates [9]

  • Between January 2010 and January 2012, 1011 patients underwent a RRP in our institution and were included in the study; no patient who underwent RRP for primary treatment of a localized prostate cancer during the period was excluded from the study

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Summary

Introduction

The number of new cases of prostate cancer worldwide is higher than 1.1 million each year, which represents 15.3% of all incident cancer cases in developed countries and 4.3% of the cases in developing countries [1]. For patients with a life expectancy exceeding 10 ibju | Predictive factors for prolonged hospital stay after retropubic radical years, radical prostatectomy (RP) continues to be one of the standard treatments [2]. The technique of retropubic radical prostatectomy (RRP) was subsequently standardized by Walsh et al [4], with significant improvement in perioperative, oncological, and functional outcomes [5]. With improvements in the anesthetic technique and intra-operative care, the mean hospitalization time has decreased [6,7,8]; subsequently, this time was further reduced by the establishment of optimized strategies for perioperative care after RRP, which resulted in short hospitalization, without an associated increase in the postoperative complication rates [9]

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