Abstract
Predictive and diagnostic value of VZV infections in HIV patients: Clinical and laboratory cross-correlations between VZV and HIV infections
Highlights
More than 95% of adults born in the United States have immunity to varicella, the vast majority due to primary varicella zoster virus (VZV) infection
The VZV infection is associated mainly with progressed immuno-suppression. (Infection lowers CD4 count and the lower CD4 count means a weaker immune system.) This important finding shows the opportunistic character of VZV infections
Herpes zoster can occur in HIV-infected adults at any CD4 T lymphocyte (CD4) cell count, but frequency of disease is highest with CD4 counts of
Summary
More than 95% of adults (aged >20 years) born in the United States have immunity to varicella, the vast majority due to primary VZV infection. People with healthy immune system can be exposed to certain viruses, bacteria, or parasites and have no reaction to them-but people living with HIV/AIDS can face serious health threats from what are known as “opportunistic” infections (OIs), including VZV , HSV and CMV. These infections are called “opportunistic” because they take advantage of their weakened immune system, and they can cause devastating illnesses. We already know that there is an association between people having had an opportunistic illness and short- and long-term effects on HIV RNA VL and CD4+ cell count
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