Abstract
Solid Organ Transplantation and HIV: A Changing Paradigm
Highlights
As early as the mid-1980s, it was apparent that HIV could be transmitted in the setting of solid organ transplantation through donor organs as well as through blood transfusions [1]
The results from a 1997 survey [2] of 248 United States (US) renal transplant centre directors, who were asked about their approach to HIV-infected patients with end-stage renal disease, can hardly be surprising
Among the 148 respondents, 84% would not transplant an individual who refused HIV testing, 88% would not transplant a cadaveric kidney into an asymptomatic HIV-infected patient with end-stage renal disease who was an otherwise good candidate for transplantation, and 91% would not transplant a living donor kidney into an asymptomatic HIV-infected individual
Summary
As early as the mid-1980s, it was apparent that HIV could be transmitted in the setting of solid organ transplantation through donor organs (living and cadaveric) as well as through blood transfusions [1]. A 2004 analysis [20] of data from the US Renal Data System (27,851 patients transplanted between January 1, 2006, and May 31, 2001; 47 [0.2%] of whom were HIVinfected) found that graft and patient survival rates were similar in HIV-infected and noninfected kidney recipients.
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