Prediction model based on artificial intelligence for identifying risk of coronary atherosclerotic heart disease in computed tomography

Abstract

ObjectiveTo analyze the application value of artificial intelligence (AI) in coronary computed tomography angiography (CCTA) image processing and diagnosis of coronary atherosclerotic heart disease (CHD). MethodsA total of 80 patients with suspected CHD in our hospital were selected for CCTA examination and blood lipid examination. The convolutional neural networks (CNN) model of coronary artery plaque detection was constructed, and the data set was randomly divided into training set and test set after pretreatment of lipid characteristics and image characteristics. The prediction efficiency and accuracy of the model were evaluated. ResultsIn the data set, the lipid indexes LDL-C, TC, and TG of patients in the CHD group were significantly higher than those in the Non-CHD group (P < 0.05). The average processing and diagnosis time of the AI model was (187.19 ± 18.79) s, which was significantly shorter than the average time of doctors (989.07 ± 50.40) s, and the difference was statistically significant (P < 0.05). There was no significant difference in the detection of calcified plaque, non-calcified plaque, and mixed plaque between doctors and AI models (P > 0.05). However, 5 plaques were misdiagnosed in the AI model (3.38%). The area under the curve (AUC) value of the CNN recognition model-based AI and manual recognition of doctors for the CHD were 0.870 (95% CI: 0.698–0.931) and 0.870 (95% CI: 0.691–0.926) (P < 0.001). ConclusionAI integrated with lipid parameters has certain clinical value in CCTA image processing efficiency and plaque diagnosis, and can be used as an effective auxiliary tool to analyze and diagnose CHD.