Abstract

Research ArticleOpen AccessPredicting chemical carcinogenesis in rodents. J T Wachsman, D W Bristol, J Spalding, M Shelby, and R W Tennant J T Wachsman National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709. Search for more papers by this author , D W Bristol National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709. Search for more papers by this author , J Spalding National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709. Search for more papers by this author , M Shelby National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709. Search for more papers by this author , and R W Tennant National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709. Search for more papers by this author Published:1 October 1993https://doi.org/10.1289/ehp.93101444Cited by:16AboutSectionsPDF ToolsDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InReddit "Predicting chemical carcinogenesis in rodents.." Environmental Health Perspectives, 101(5), pp. 444–445FiguresReferencesRelatedDetailsCited By Greene N (2007) Computational Models to Predict Toxicity Comprehensive Medicinal Chemistry II, 10.1016/B0-08-045044-X/00155-3, (909-932), . Ward E, Schulte P, Bayard S, Blair A, Brandt-Rauf P, Butler M, Dankovic D, Hubbs A, Jones C, Karstadt M, Kedderis G, Melnick R, Redlich C, Rothman N, Savage R, Sprinker M, Toraason M, Weston A, Olshan A, Stewart P and Zahm S (2018) Priorities for development of research methods in occupational cancer., Environmental Health Perspectives, 111:1, (1-12), Online publication date: 1-Jan-2003. Ward E, Schulte P, Bayard S, Blair A, Brandt-Rauf P, Butler M, Dankovic D, Hubbs A, Jones C, Karstadt M, Kedderis G, Melnick R, Redlich C, Rothman N, Savage R, Sprinker M, Toraason M and Weston A (2002) Priorities for Development of Research Methods in Occupational Cancer, Environmental Health Perspectives, 10.1289/ehp.5537, 111:1, (1-12) Woo Y and Lai D (2001) Structure–Activity Relationship (SAR) and Its Roles in Cancer Risk Assessment Genetic Toxicology and Cancer Risk Assessment, 10.1201/9780203904237.ch4, (73-91), Online publication date: 31-Aug-2001. Richard A (1998) Structure-based methods for predicting mutagenicity and carcinogenicity: are we there yet?, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 10.1016/S0027-5107(98)00068-2, 400:1-2, (493-507), Online publication date: 1-May-1998. Schwetz B and Gaylor D (2018) Alternative tests: carcinogenesis as an example., Environmental Health Perspectives, 106:suppl 2, (467-471), Online publication date: 1-Apr-1998. Schwetz B and Gaylor D (1997) New directions for predicting carcinogenesis, Molecular Carcinogenesis, 10.1002/(SICI)1098-2744(199711)20:3<275::AID-MC3>3.0.CO;2-K, 20:3, (275-279), Online publication date: 1-Nov-1997. Benigni R and Richard A (1996) QSARS of mutagens and carcinogens: Two case studies illustrating problems in the construction of models for noncongeneric chemicals, Mutation Research/Genetic Toxicology, 10.1016/S0165-1218(96)90092-0, 371:1-2, (29-46), Online publication date: 1-Nov-1996. McKinney J (2018) Reactivity parameters in structure-activity relationship-based risk assessment of chemicals., Environmental Health Perspectives, 104:8, (810-816), Online publication date: 1-Aug-1996.Bristol D, Wachsman J and Greenwell A (2018) The NIEHS Predictive-Toxicology Evaluation Project., Environmental Health Perspectives, 104:suppl 5, (1001-1010), Online publication date: 1-Oct-1996.Marchant C (2018) Prediction of rodent carcinogenicity using the DEREK system for 30 chemicals currently being tested by the National Toxicology Program. The DEREK Collaborative Group., Environmental Health Perspectives, 104:suppl 5, (1065-1073), Online publication date: 1-Oct-1996.Tennant R and Spalding J (2018) Predictions for the outcome of rodent carcinogenicity bioassays: identification of trans-species carcinogens and noncarcinogens., Environmental Health Perspectives, 104:suppl 5, (1095-1100), Online publication date: 1-Oct-1996.Huff J, Weisburger E and Fung V (2018) Multicomponent criteria for predicting carcinogenicity: dataset of 30 NTP chemicals., Environmental Health Perspectives, 104:suppl 5, (1105-1112), Online publication date: 1-Oct-1996. Woo Y, Lai D, Argus M and Arcos J (1995) Development of structure-activity relationship rules for predicting carcinogenic potential of chemicals, Toxicology Letters, 10.1016/0378-4274(95)03373-S, 79:1-3, (219-228), Online publication date: 1-Sep-1995. Bristol D (1995) Summary and recommendations for session B: activity classification and structure-activity relationship modeling for human health risk assessment of toxic substances, Toxicology Letters, 10.1016/0378-4274(95)03377-W, 79:1-3, (265-280), Online publication date: 1-Sep-1995. Haseman J (2014) Animal Screening Systems Wiley StatsRef: Statistics Reference Online, 10.1002/9781118445112.stat05460 Vol. 101, No. 5 October 1993Metrics About Article Metrics Publication History Originally published1 October 1993Published in print1 October 1993 Financial disclosuresPDF download License information EHP is an open-access journal published with support from the National Institute of Environmental Health Sciences, National Institutes of Health. All content is public domain unless otherwise noted. Note to readers with disabilities EHP strives to ensure that all journal content is accessible to all readers. 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