Abstract
Umbelliferae (Apiaceae) is a large family containing mainly coumarins and volatile oils. Ferulago platycarpa Boiss. & Bal. is a perennial endemic species growing in Nevsehir, Turkey [1]. In addition, species of the genera Ferula and Prangos are also known by these names, and although they have other usages, they are, mainly used as aphrodisiacs in Turkey [2]. In this study, we determined the prantschimgin content of methanolic extracts obtained from the roots of F. platycarpa by HPLC. Prantschimgin was identified for the first time from Prangos tschimganica B. Fedtsch [3] and, among the Ferulago genus, for the first time from the roots of F. meioides (L.) Boiss. [4]. It is reported to be present in some other Ferulago species as well [5–8]. It has a furocoumarin structure and is found to be the major component of the roots of the methanolic extract of F. platycarpa. By using the calibration curve that we obtained with the standard substance, we determined the prantschimgin content of the methanolic extract of the roots to be 1.90%. When we compared this value with other Ferulago species, we found, for F. meoides [4]: a coumarin mixture (15 g) was obtained from 500 g roots, which yielded 4 fractions. Fraction II weighed
Published Version
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