Abstract

Click on the links below to access all the ArticlePlus for this article.Please note that ArticlePlus files may launch a viewer application outside of your web browser.PRACTICE advisories are systematically developed reports that are intended to assist decision-making in areas of patient care where scientific evidence is insufficient to develop an evidence-based model. Practice advisories provide a synthesis of opinion from experts, open forums, and other public sources. Practice advisories report the current state of scientific literature, but are not supported by literature to the same degree as standards or guidelines due to the lack of sufficient numbers of adequately controlled studies.Advisories are not intended as guidelines, standards, or absolute requirements. The use of practice advisories cannot guarantee any specific outcome. They may be adopted, modified, or rejected according to clinical needs and constraints. Practice advisories are subject to periodic revision as warranted by the evolution of medical knowledge, technology, and practice.The literature does not provide a standard definition for preanesthesia evaluation. For this Practice Advisory, the preanesthesia evaluation is defined as the process of clinical assessment that precedes the delivery of anesthesia care for surgery and for nonsurgical procedures. The preanesthesia evaluation is the responsibility of the anesthesiologist.Preanesthesia evaluation consists of the consideration of information from multiple sources that may include the patient's medical records, interview, physical examination, and findings from medical tests and evaluations. As part of the preanesthesia evaluation process, the anesthesiologist may choose to consult with other healthcare professionals to obtain information or services that are relevant to perioperative anesthetic care. Preoperative tests, as a component of the preanesthesia evaluation, may be indicated for various purposes, including but not limited to (1) discovery or identification of a disease or disorder that may affect perioperative anesthetic care, (2) verification or assessment of an already known disease, disorder, medical or alternative therapy that may affect perioperative anesthetic care, and (3) formulation of specific plans and alternatives for perioperative anesthetic care. For this Advisory, perioperative refers to the care surrounding operations and procedures.The assessments made in the process of a preanesthesia evaluation may be used to educate the patient, organize resources for perioperative care, and formulate plans for intraoperative care, postoperative recovery, and perioperative pain management.The purposes of this Advisory are to (1) assess the currently available evidence pertaining to the healthcare benefits of preanesthesia evaluation, (2) offer a reference framework for the conduct of preanesthesia evaluation by anesthesiologists, and (3) stimulate research strategies that can assess the healthcare benefits of a preanesthesia evaluation.A preanesthesia evaluation is considered a basic element of anesthesia care. Therefore, the focus of this Advisory is the assessment of evidence pertaining to the content and timing of a preanesthesia evaluation. The interactions between the preanesthesia evaluation, preoperative testing, and perioperative care are beyond the scope and mandate of the Task Force. Informed consent, often undertaken at the same time as the preanesthesia evaluation, is also beyond the scope of this Advisory.This Advisory is intended for use by anesthesiologists and those who provide care under the direction of an anesthesiologist. The Advisory applies to patients of all ages who are scheduled to receive general anesthesia, regional anesthesia, moderate or deep sedation for elective surgical and nonsurgical procedures. The Advisory does not address the selection of anesthetic technique nor the preanesthesia evaluation of patients requiring urgent or emergency surgery or anesthetic management provided on an urgent basis in other locations (e.g. , emergency rooms).Any evaluations, tests, and consultations required for a patient are done with the reasonable expectation that such activities will result in benefits that exceed the potential adverse effects. Potential benefits may include a change in the content or timing of anesthetic management or perioperative resource utilization that may improve the safety and effectiveness of anesthetic processes involved with perioperative care. Potential adverse effects may include interventions that result in injury, discomfort, inconvenience, delays, or costs that are not commensurate with the anticipated benefits.The American Society of Anesthesiologists (ASA) appointed a task force of 12 members to (1) review published evidence; (2) obtain expert and public consensus opinion; and (3) create a consensus-based assessment of currently available scientific literature and opinion. The ASA Task Force members consisted of anesthesiologists in both private and academic practices from various geographic areas of the United States, and methodologists from the ASA Committee on Practice Parameters.The Task Force used a six-step process. First, they reached consensus on the criteria for evidence of effectiveness of preanesthesia evaluation. Second, original published research studies relevant to these issues were reviewed. Third, consultants who had expertise or interest in preanesthesia evaluation, and who practiced or worked in various settings (e.g. , academic and private practice) were asked to (1) participate in opinion surveys on the effectiveness of various preanesthesia evaluation strategies, and (2) review and comment on draft reports of the Task Force. Fourth, opinions about various elements of this Practice Advisory were solicited from a random sample of active members of the ASA. Fifth, the Task Force held several open forums at major national anesthesia meetings to solicit input on the key concepts of this Advisory. Sixth, all available information was used to build consensus within the Task Force on the Advisory.Practice advisories are developed by a systematic, consensus-based process. In contrast to evidence-based guidelines, practice advisories lack the support of a sufficient number of adequately controlled scientific studies to permit aggregate analyses of data with rigorous statistical techniques such as meta-analysis. Nonetheless, literature-based evidence for practice advisories is available from limited controlled trials, case reports, descriptive studies, and by the assessment of the strengths and weaknesses of published studies. This literature often permits the identification of recurring patterns of clinical practice. Opinion surveys often reveal similar patterns. The advisory statements contained in a practice advisory represent a consensus-based distillation of the clearest patterns of agreement or disagreement.A preanesthesia history and physical examination precedes the ordering, requiring, or performance of specific preanesthesia tests, and consists of (1) evaluation of pertinent medical records, (2) patient interview(s), and (3) physical examination. No controlled trials of the clinical impact of performing a preanesthesia medical records review or physical examination were found. Several studies reported specific perioperative outcomes (e.g. , cardiac, respiratory, renal, hemorrhagic) occurring in patients with specific preexisting conditions (e.g. , hypertension, previous myocardial infarction, smoking, pulmonary disease, and age). 1–63Such conditions often are noted in a patient's medical record. Additional studies were examined that reported preexisting conditions (e.g. , airway abnormalities, cardiopulmonary disorders) detected during a preanesthesia examination or interview. 6,28,44,47,49,59,64–91Five of these studies resulted in changes in resource management. 49,64,74,82,84These studies were not controlled trials and were not considered sufficiently rigorous to provide unequivocal evidence of the value of performing a preanesthetic medical records review or physical examination.The Task Force believes that the assessment of anesthetic risks associated with the patient's medical conditions, therapies, alternative treatments, surgical and other procedures, and of options for anesthetic techniques is an essential component of basic anesthetic practice. Benefits may include, but are not limited to, the safety of perioperative care, optimal resource utilization, improved outcomes, and patient satisfaction.The activities encompassed by a preanesthesia history and physical examination occur over a variable period of time. The timing of an initial preanesthesia evaluation is guided by such factors as patient demographics, clinical conditions, type and invasiveness of procedure, and the nature of the healthcare system. Three options that practices utilize for the timing of an initial preanesthesia evaluation are (1) always prior to the day of surgery, (2) either on or before the day of surgery, and (3) only on the day of surgery.Although no controlled trials addressing the timing of a preanesthesia evaluation were found, survey opinions from expert consultants and a random sample of ASA members were obtained to examine potential clinical influences (i.e. , patient severity of disease and surgical invasiveness) on timing decisions. Consultant and ASA member opinions regarding the timing of an initial assessment of pertinent medical records for high, medium, and low levels of surgical invasiveness, independent of medical condition, are reported in table 1. The majority of consultants and ASA members agree that, for high surgical invasiveness, the initial assessment of pertinent medical records should be done prior to the day of surgery by anesthesia staff. For medium surgical invasiveness, the majority of consultants indicate that the initial assessment of pertinent medical records should be done prior to the day of surgery by anesthesia staff, although the majority of ASA members indicate that the initial assessment may be done on or before the day of surgery. For low surgical invasiveness, the majority of consultants and ASA members agree that the initial assessment may be done on or before the day of surgery.Consultant and ASA membership opinions regarding the timing of an initial preanesthesia interview and physical examination for high and low severities of disease are reported in table 2. The majority of consultants and ASA members agree that, for patients with high severity of disease, it is preferable that the interview and physical examination be done before the day of surgery by anesthesia staff. For low severity of disease and high surgical invasiveness, consultants and ASA members agree that it is preferable that the interview and physical examination be done prior to the day of surgery. For patients with low severity of disease and medium or low surgical invasiveness, consultants and ASA members agree that the interview and physical examination may be done on or before the day of surgery.A majority of consultants and the ASA membership, respectively, agree that, at a minimum , a preanesthesia physical examination should include (1) an airway exam (100%, 100%), (2) a pulmonary examination to include auscultation of the lungs (88%, 85%), and (3) a cardiovascular examination (81%, 82%).The Task Force consensus is that an assessment of readily accessible, pertinent medical records with consultations, when appropriate, should be performed as part of the preanesthesia evaluation prior to the day of surgery for procedures with high surgical invasiveness. For procedures with low surgical invasiveness, the review and assessment of medical records may be done on or before the day of surgery by anesthesia staff. The information obtained may include, but should not be limited to (1) a description of current diagnoses, (2) treatments, including medications and alternative therapies used, and (3) determination of the patient's medical condition(s). Public commentary at open forums and from the Internet corroborates the Task Force consensus.The Task Force consensus is that an initial record review, patient interview, and physical examination should be performed prior to the day of surgery for patients with high severity of disease. For patients with low severity of disease and undergoing procedures with high surgical invasiveness, the interview and physical exam should also be performed prior to the day of surgery. For patients with low severity of disease undergoing procedures with medium or low surgical invasiveness, the initial interview and physical exam may be performed on or before the day of surgery.At a minimum , a focused preanesthesia physical examination should include an assessment of the airway, lungs, and heart, with documentation of vital signs. Public commentary at open forums and from the Internet corroborate the Task Force opinions.The Task Force cautions that timing of preanesthesia assessments may not be practical with the current limitation of resources provided by a specific healthcare system or practice environment. The Task Force believes it is the obligation of the healthcare system to, at a minimum, provide pertinent information to the anesthesiologist for the appropriate assessment of the severity of the medical condition of the patient and invasiveness of the proposed surgical procedure well in advance of the anticipated day of the procedure for all elective patients.Literature regarding controlled trials and test findings regarding the incidence or frequency of commonly used preoperative tests are described below. For purposes of this Advisory, a routine test is defined as a test ordered in the absence of a specific clinical indication or purpose. Global designations such as “preop status” or “surgical screening” are not considered as specific clinical indications or purposes. An indicated test is defined as a test that is ordered for a specific clinical indication or purpose. For example, assessment of warfarin therapy effects would be considered an indication for specific coagulation studies.Routine electrocardiographic findings were reported as abnormal in 7.0–42.7% of cases (N = 12 studies) 92–103and led to changes in clinical management in 9.1% of the cases found to be abnormal (N = 1 study). 100Preoperative electrocardiograms that were ordered as indicated tests resulted in reports of abnormal findings in 4.8–78.8% of cases (N = 17 studies) 49,51,82,100,104–116and led to changes in clinical management in 2.0–20.0% of the cases found to be abnormal (N = 6 studies). 49,82,100,104,111,112One observational study with investigator and practitioner blinding found that preoperative electrocardiographic ischemic episodes were associated with intra- and-postoperative myocardial infarction for older patients with severe coronary artery disease scheduled for elective coronary artery bypass grafting (CABG). 110One observational study reported a 10% or greater incidence of coronary events during the subsequent 10 yr for men over 60 without specific clinical indicators and for women over 65 without specific clinical indicators. The incidence increased to 25% in the decade after such patients’ seventy-fifth birthday. 107No studies were found that examined outcomes from routine preoperative cardiac evaluations of angiography, echocardiography, or stress tests. For patients with indicated cardiac evaluations, abnormal findings were found with angiography: 22.5–47.0% of cases (N = 4 studies) 117–120; echocardiography: 7.5%-50.0% of cases (N = 5 studies) 121–125; stress or exercise tests; 15.0–71.0% of cases (N = 3 studies). 105,126,127Changes in clinical management were not uniformly reported.Routine chest x-ray findings were reported as abnormal in 2.5–60.1% of cases (N = 20 studies) 96,98,100,102,128–142and led to changes in clinical management in 0–51% of the cases found to be abnormal (N = 9 studies). 100,102,128,129,136,139–142For patients with indicated preoperative chest x-rays, abnormal findings were reported in 7.7–65.4% of cases (N = 18 studies) 30,82,92,100,106,112,128,137,143–152and led to changes in clinical management in 0.5–74.3% of the cases found to be abnormal (N = 9 studies). 82,100,112,128,143,145–147,152Two nonrandomized studies compared asymptomatic patients receiving chest x-rays versus asymptomatic patients not receiving chest x-rays and found no differences in delays or cancellations of surgery. 141,142However, the studies found that an abnormal preoperative chest x-ray finding altered care in 8.6% and 9.9% of the cases found to be abnormal.Studies examining routine pulmonary function tests (PFT's) did not contain data on abnormal findings (N = 2). 46,153Studies examining routine preoperative spirometry reported abnormal findings in 15.0–51.7% of cases (N = 3 studies). 154–156Findings for indicated preoperative PFT's were reported as abnormal in 17.0–27.1% of cases (N = 3 studies), 157–159and indicated preoperative spirometry (a limited form of PFT's) were reported as abnormal in 33.1–45.0% of cases (N = 3 studies). 30,157,160Changes in clinical management were not reported. No studies were found that reported results of routine preanesthesia office spirometry (i.e. , portable or hand held spirometers).Routine hemoglobin measurements were reported as abnormal in 0.5–43.8% of cases (N = 7 studies) 102,133,161–165and led to changes in clinical management in 0%-28.6% of the cases found to be abnormal (N = 3 studies). 102,161,164Indicated hemoglobin measurements were reported as abnormal in 38.6–62.0% of cases (N = 2 studies). 166,167Changes in clinical management were not reported.Routine hematocrit measurements were reported as abnormal in 0.2–38.9% of cases (N = 5 studies) 136,162,168–170and led to changes in clinical management in 0–100% of the cases found to be abnormal (N = 3 studies). 136,168,170Indicated hematocrit measurements were reported as abnormal in 0.4–5.0% of cases (N = 2 studies). 51,148Changes in clinical management were not reported.In studies reporting routine complete blood counts (i.e. , individual test results not reported), abnormal findings were reported in 2.9–17.6% of cases (N = 4 studies) 92,98,171–172and led to changes in clinical management in 2.4% of the cases found to be abnormal (N = 1 study). 172For indicated complete blood counts, abnormal findings were reported in 6.3–60.8% of cases (N = 4 studies) 92,107,108,112and led to changes in clinical management in 0.0%-14.9% of the cases found to be abnormal (N = 2 studies). 108,112Routine coagulation studies reported abnormalities in bleeding time, prothrombin time, partial prothrombin time, or platelet count in 0.8–22.0% of cases (N = 15 studies) 13,136,162,173–184and led to changes in clinical management in 1.1–4.0% of the cases found to be abnormal (N = 2 studies). 13,136Findings for indicated coagulation studies were reported as abnormal in 3.4–29.1% of cases (N = 4 studies). 183,185–187Changes in clinical management were not reported. The incidence of routine coagulation study abnormalities in patients scheduled for regional anesthesia or postoperative analgesia in surgical patients has not been reported. The incidence of routine coagulation study abnormalities in obstetric patients has not been reported.In routine preoperative potassium tests, abnormal levels of potassium were found in 1.5–12.8% of cases (N = 3 studies). 133,162,188For indicated potassium tests, abnormal levels were found in 1.0–29.5% of cases (N = 4 studies). 51,148,189,190One randomized clinical trial compared preoperative serum potassium levels at induction with serum potassium levels 3 days before surgery, and found lower potassium levels (hypokalemia) at induction. 188No blinded studies were found that assessed the benefits or harms of practitioner awareness of potassium abnormalities.In routine preoperative glucose tests in nondiabetic patients or patients without altered glucose metabolism, abnormal levels of glucose were found in 5.4–13.8% of cases (N = 3 studies). 133,162,171Changes in clinical management were not reported.In routine preoperative urinalysis (not including pregnancy testing), abnormal results were reported in 0.7–38.0% of cases (N = 9 studies) 92,96,102,136,162,170,172,191,192and led to changes in clinical management in 2.3–100% of the cases found to be abnormal (N = 6 studies). 102,136,170,172,191,192For indicated urinalysis, abnormal results were found in 4.6–42.0% of cases (N = 4 studies) 92,108,112,148and led to changes in clinical management in 0.0–23.1% of the cases found to be abnormal (N = 2 studies). 108,112Routine pregnancy tests (routine refers to premenopausal menstruating females, not excluding anyone on the basis of history) resulted in positive findings in 0.3–2.2% of cases (N = 5 studies) 193–197and led to changes in clinical management, delays or cancellation of surgery in 100% of the cases found to be pregnant.Consultants and ASA members were asked to consider whether specific preoperative tests should be conducted (1) on a routine basis (i.e. , given to patients regardless of known or suspected diseases or disorders), (2) for selected patients or for selected types of surgery, or (3) the test is not necessary. For the tests considered, consultant and ASA membership responses are reported in table 3. Consultants and ASA members were also asked to identify specific patient characteristics that would favor a decision to order, require, or perform a preoperative test. For these specific patient characteristics, consultant and ASA membership responses are reported in table 4.Consultants and ASA members were asked whether selected preoperative tests are acceptable if obtained from the patient's medical chart, assuming the patient's medical history has not changed substantially since the test was obtained. Majority opinions of consultants and ASA members are reported as percentage agreement, respectively, as follows:Respondents who agreed that test findings might be obtained from a patient's medical chart were asked how recent the findings should be in order to be acceptable. Opinions on how recent test findings should be are reported in table 5.The current literature is not sufficiently rigorous to permit an unambiguous assessment of the clinical benefits or harms of routine preoperative tests. The studies examined by the Task Force reported a wide range of abnormal results associated with preoperative testing. When abnormal or positive results were found, the percentage of patients with subsequent changes in their clinical management varied widely.The Task Force agrees with the consultants and ASA members that preoperative tests should not be ordered routinely. The Task Force agrees that preoperative tests may be ordered, required, or performed on a selective basis for purposes of guiding or optimizing perioperative management. The indications for such testing should be documented and based on information obtained from medical records, patient interview, physical examination, and type and invasiveness of the planned procedure. Public commentary from open forums corroborates the Task Force consensus.The current literature is not sufficiently rigorous to permit an unambiguous assessment of the clinical benefits or harms associated with selected preoperative test findings. The studies examined by the Task Force reported a wide range of abnormal preoperative test results. In addition, when abnormal or positive results were found, the percentage of patients with subsequent changes in their clinical management varied widely. Few randomized controlled trials were found that examined the outcomes for patients who had routine preoperative tests compared with outcomes for patients with indicated preoperative tests. 198The Task Force believes that there is insufficient evidence to identify explicit decision parameters or rules for ordering preoperative tests on the basis of specific clinical characteristics. However, the Task Force believes that consideration of selected clinical characteristics may assist the anesthesiologist when deciding to order, require, or perform preoperative tests. The following clinical characteristics may be of merit, although anesthesiologists should not limit their consideration only to those suggested below.The Task Force agrees that important clinical characteristics may include cardiocirculatory disease, respiratory disease, and type or invasiveness of surgery. The Task Force recognizes that electrocardiogram abnormalities may be higher in older patients and in patients with multiple cardiac risk factors.No consensus was obtained from the consultants and ASA membership regarding a minimum age for obtaining a preanesthesia electrocardiogram. The Task Force did not reach consensus on a specific minimum age in those patients without specific risk factors. The Task Force recognizes that age alone may not be an indication for an electrocardiogram. The Task Force agrees that an electrocardiogram may be indicated for patients with known cardiovascular risk factors or for patients with risk factors identified in the course of a preanesthesia evaluation.Preanesthesia cardiac evaluation may include consultation with specialists and ordering, requiring, or performing tests that range from noninvasive passive or provocative screening tests (e.g. , stress testing) to noninvasive and invasive assessment of cardiac structure, function, and vascularity (e.g. , echocardiogram, radionucleotide imaging, cardiac catheterization). Anesthesiologists should balance the risks and costs of these evaluations against their benefits. Clinical characteristics to consider include cardiovascular risk factors and type of surgery.Clinical characteristics to consider include smoking, recent upper respiratory infection, chronic obstructive pulmonary disease (COPD), and cardiac disease. The Task Force recognizes that chest radiographic abnormalities may be higher in such patients, but does not believe that extremes of age, smoking, stable COPD, stable cardiac disease, or resolved recent upper respiratory infection should be considered unequivocal indications for chest radiography.Preanesthesia pulmonary evaluation other than chest x-ray may include consultation with specialists and tests that range from noninvasive passive or provocative screening tests (e.g. , pulmonary function tests, spirometry, pulse oximetry) to invasive assessment of pulmonary function (e.g. , arterial blood gas). Anesthesiologists should balance the risks and costs of these evaluations against their benefits. Clinical characteristics that the Task Force believes should be considered include type and invasiveness of the surgical procedure, interval from prior evaluation, treated or symptomatic asthma, symptomatic COPD, and scoliosis with restrictive function.The Task Force believes that routine hemoglobin or hematocrit is not indicated. Clinical characteristics to consider as indications for such tests include type and invasiveness of procedure, patients with liver disease, extremes of age, history of anemia, bleeding, and other hematologic disorders.Clinical characteristics to consider for ordering selected coagulation studies include bleeding disorders, renal dysfunction, liver dysfunction, and type and invasiveness of procedure. The Task Force recognizes that anticoagulant medications and alternative therapies may present an additional perioperative risk. The Task Force believes that there were not enough data to comment on the advisability of coagulation tests before regional anesthesia. The Task Force strongly recommends appropriately controlled studies of such specific indications.The Task Force recognizes that laboratory values may differ from normal values at extremes of age. Clinical characteristics to consider before ordering such tests include likely perioperative therapies, endocrine disorders, risk of renal and liver dysfunction, and use of certain medications or alternative therapies.The consensus of the Task Force is that urinalysis is not indicated except for specific procedures (e.g. , prosthesis implantation, urologic procedures) or when urinary tract symptoms are present.The Task Force recognizes that a history and physical examination may be insufficient for identification of early pregnancy. Pregnancy testing may be considered for all female patients of childbearing age. Clinical characteristics to consider include an uncertain pregnancy history or a history suggestive of current pregnancy.The current literature is not sufficiently rigorous to permit an unambiguous assessment of the clinical benefits or harms of the timing for preoperative tests. The Task Force believes that there is insufficient evidence to identify explicit decision parameters or rules for ordering preoperative tests on the basis of specific patient factors.The Task Force believes that test results obtained from the medical record within 6 months of surgery are generally acceptable if the patient's medical history has not changed substantially. More recent test results may be desirable when the medical history has changed, or when test results may play a role in the selection of a specific anesthetic technique (e.g. , regional anesthesia in the setting of anticoagulation therapy.) Public commentary from open forums and from the Internet corroborates the Task Force consensus.A preanesthesia evaluation involves the assessment of information from multiple sources, including medical records, patient interviews, physical examinations, and findings from preoperative tests.The current scientific literature does not contain sufficiently rigorous information about the components of a preanesthesia evaluation to permit recommendations that are unambiguously based. Therefore, the Task Force has relied primarily upon noncontrolled literature, opinion surveys of consultants, and opinion surveys of a random sample of members of the ASA. The focus of opinion surveys has been threefold (1) the content of the preanesthesia evaluation, (2) the timing of the preoperative evaluation, and (3) the indications for specific preoperative tests.The following remarks represent a synthesis of the opinion surveys, literature and Task Force consensus:The references listed here do not represent a complete bibliography of the literature reviewed. A complete bibliography is available by writing to the American Society of Anesthesiologists or by accessing the Anesthesiology Web site:http://www.anesthesiology.org.

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