Abstract
The body’s natural ageing process is characterised by a decrease in skin volume and the development of deeper wrinkles. Fillers derived from cross-linked hyaluronic acid are commonly used in aesthetic medicine procedures, however they are frequently overused. Current investigations are underway to new solutions that can be utilised in therapies aimed at regenerating damaged tissues and enhancing the appearance of the skin. Collagen stimulators, which include both type I and type III, consist of amino acids, fragmented uncrosslinked hyaluronic acid, biomimetic peptides, polynucleotides, and polymers. The above compounds serve as alternatives to crosslinked hyaluronic acid. This study aimed to introduce powdered polydioxanone containing microspheres as a product that promotes the production of collagen. This synthetic polymer can be used by patients seeking to rejuvenate facial skin by restoring its tone, density, and natural volume. Due to its hydrophilic properties, immune neutrality, and ability to degrade into water and carbon dioxide, powdered polydioxanone seems to be a safe option for aesthetic medicine procedures.
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