Abstract
In this work, a turn-off sensing approach for simple and sensitive determination of tyrosine is developed on the basis of quenching of fluorescence of carbon dot. When carbon dot is mixed with potassium triiodide, the fluorescence of carbon dot undergo quenching and this quenching phenomena get enhanced in the presence of tyrosine. The possible interfering amino acids and biomolecules exhibit turn-on behaviour and thus tyrosine has good selectivity. The limit of detection of tyrosine is 950 nM. Real sample analysis in serum sample shows good recovery percentage.
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