Abstract

The wound care market is rapidly expanding due to the development of innumerable dressings that exhibit specific healing requirements for different wound types. The use of biomaterials as suitable wound dressing material is highly advantageous due to their biocompatibility, biodegradability, and non-toxicity. Cyanobacteria have been widely explored for their potential applications in wound healing, as they are the rich source of bioactive compounds with antibacterial, antitumor, antiviral, antioxidant, and antifungal activities. In recent years this group of organisms has been widely studied due to their immense potential in biomedical applications. Although their different bioactivities can support wound healing in different ways, very few forms have proven utility as a wound-healing agent. This chapter gives an insight into the potential of cyanobacteria in wound healing. Different bioactive compounds present in variable forms of cyanobacteria and their associated activities were reported to support tissue regeneration and wound healing acceleration. As the demand for cost-effective, bioactive wound care products is ever increasing, these organisms have immense potential to be utilized for the development of bioactive wound dressings. Hence, various bioactive compounds of cyanobacteria, their associated activities, and roles in wound healing have been briefly reviewed in this chapter.

Highlights

  • Wound healing involves various interactions between cellular, molecular, biochemical, and physiological activities, making the process very complex, dynamic, and precisely programmed

  • Various synthetic and natural products have been widely explored for their efficiency and accelerating wound healing abilities to accomplish the need for suitable dressing for a particular wound type

  • Many cyanobacterial compounds have been reported to possess inhibitory effects against different pathogenic strains of fungi [36]. They are an excellent source of various bioactive compounds that belong to several different chemical classes like peptides, polyketides, and alkaloids [37]

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Summary

Introduction

Wound healing involves various interactions between cellular, molecular, biochemical, and physiological activities, making the process very complex, dynamic, and precisely programmed. Produced secondary metabolites are low molecular weight, natural organic compounds, essential for average growth and development of these organisms These metabolites have a wide range of applications in the field of medicines, industries, and biotechnology. In the last few decades, cyanobacteria have gained lots of attention for their medicinal values and wound healing properties They are the choice of organisms due to their easy availability, fast regeneration, and huge diversity which have further expanded interest of researchers in their values as medicine and functional foods [9]. Cyanobacterial secondary metabolites show different medicinally essential activities such as antitumor, antibacterial, antifungal, antiviral, anti-inflammatory, immunomodulatory effects, and protease inhibition [10] These biological activities are helpful to promote wound healing in different ways. We present an overview of bioactive compounds of cyanobacteria responsible for their various biological activities that promote the wound healing process by affecting different phases and factors of wound healing

Antibacterial activity
Antifungal activity
Antioxidant activity
Immunomodulatory and anti-inflammatory effects
Hemostatic activity
Wound healing effect of cyanobacteria
Conclusions
Findings
Conflict of interest
Full Text
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