Abstract

Transverse myelitis (TM) is a clinical syndrome in which an inflammatory process injures the spinal cord potentially resulting in weakness, sensory abnormalities and autonomic dysfunction. The main causes are post-infectious, post-vaccination, autoimmune and demyelinating diseases. In a literature review based on five cases of TM during pregnancy and puerperal period have been reported. We report a female patient in the immediate postpartum period who presented acute transverse myelites after receiving double viral vaccine (measles and rubella). After exclusion of other causes, patient received methylprednisolone in high doses ( 1000 mg for 3 consecutives days) and had complete clinical reversal. Thus it is intended to report this rare occurrence which is post-vaccination TM in the postpartum period.

Highlights

  • Transverse myelitis (TM) is a rare syndrome that presents with neurological deficits secondary to an inflammatory process that causes lesions, acute or subacute, in the spinal cord potentially resulting in weakness, sensorial alterations and autonomic dysfunction[1]

  • Transverse myelitis syndrome arise from various causes, but it most often occurs as an autoimmune phenomenon after an infection or vaccination[3]

  • Not being found secondary causes of TM, we considered the diagnosis of post-vaccination myelitis The patient received treatment with high dose corticosteroids (1000 mg methylprednisolone) for 3 days

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Summary

INTRODUCTION

Transverse myelitis (TM) is a rare syndrome that presents with neurological deficits secondary to an inflammatory process that causes lesions, acute or subacute, in the spinal cord potentially resulting in weakness, sensorial alterations and autonomic dysfunction[1]. Not being found secondary causes of TM, we considered the diagnosis of post-vaccination myelitis The patient received treatment with high dose corticosteroids (1000 mg methylprednisolone) for 3 days. The patient had a good response, with full recovery of strength, sphincter control and sensitive symptoms. It was discharged 23 days after the event for outpatient follow

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