Abstract
Purpose: The purpose of this study was to evaluate the clinical impact of postprocedural TIMI flow in an infarct-related artery (IRA) on outcomes in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary revascularization. Methods: A total of 2767 patients with NSTEMI enrolled in the Polish Registry of Acute Coronary Syndromes (PL-ACS) who underwent an invasive strategy with percutaneous coronary intervention (PCI) were analyzed. Patients were divided in 3 groups according to postprocedural culprit vessel TIMI flow (TIMI 0/1: 90 patients - 3,26%, TIMI 2: 61 patients - 2,20%, TIMI 3: 2616 patients - 94,54%). Results: The in-hospital mortality for the TIMI 0/1, TIMI 2 and TIMI 3 was adequately 12,22% vs 13,11% vs 3,44% (p 0, higher ejection fraction and family history of CAD. While the lesion type C, heart failure in history and PCI without stenting independly predict suboptimal TIMI flow grade 0-2. Conclusions: In patients with NSTEMI treated with PCI postprocedural TIMI flow was strongly associated with in-hospital and long-term mortality. Interestingly, mortality rate among patients with near-normal TIMI 2 flow is comparable to patients with TIMI flow grade 0-1 after percutaneous intervention.
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