Postoperative nutritional effects of early enteral feeding compared with total parental nutrition in total gastrectomy patients

Abstract

Objective To compare the effect of comparion of the effect of postoperative.Methods Forty patients with total gastrectomy for gastric cancer surgery were randomly divided into groups of early parenteral nutrition (EEN) and total parental nutrition (TPN) group,20 patients in each group.Nutritional index,immune status,complication rate and postoperative intestinal function recovery time and average hospital stay were observed.Results The first day of bowel movement and time to take a normal soft diet was significantly shorter in EEN group than that in TPN group(t =5.091,7.007,all P ＜ 0.05).and the hospital stays of EEN group all so significantly shorter than TPN group (t =5.802,P ＜ 0.05).Prealbumin and transferrin were significantly reduced on post-operative day (POD)7 and were slowly recovered until POD 90.but the increased rate in EEN group was significantly faster than that in TPN group [cprealbumin:t =9.501,7.913,7.182,6.154,all P ＜ 0.05] ; transferrin:t =5.501,5.712,5.733,5.801,all P ＜ 0.05).The TLC,CD4 and CD8 are lower than before total gastrectomy on POD 7,and have been recovered to the level before surgery.The TLC level on POD 7 and 14 were significantly higher in EEN group than that in TPN group (t =5.645,5.134,all P ＜ 0.05).The PG-SGA score was lower in EEN group than that in TPN group,particularly on POD 21 (t =5.211,P ＜ 0.05).Conclusion Total gastreetomy for gastric cancer after curative resection of early enteral nutrition support can improve the postoperative intestinal function recovery and shorten the time of hospital stay for patients. Key words: Enteral nutrition; Parenteral nutrition; Gastrectomy; Stomach neoplasms