Postoperative analgesic effects of ultrasound guided transversus abdominis plane block combined with intravenous parecoxib sodium on laparoscopic myomectomy

Abstract

Objective To study the postoperative analgesic effects of transversus abdominis plane(TAP) block combined with parecoxib sodium intravenous injection on laparoscopic myomectomy. Methods Eighty patients underwent laparoscopic myomectomy were randomly divided into the combination analgesia group and the intravenous analgesia group. The patients in the combined analgesia group were treated with intravenous injection of parecoxib before anesthesia induction, combined with ultrasound guided TAP block after anesthesia induction and before skin incision, and received sufentanil patient-controlled intravenous analgesia postoperatively in the intravenous analgesia group. VAS and comfort score (BCS) were recorded at 1, 4, 8, 12 and 24 h after the operation. The incidence of adverse reactions was also recorded in the two groups. Results VAS was lower and BCS was higher at 1, 4 h in the combined analgesia group than those in the intravenous analgesia group (P<0.05). There was no significant difference for VAS and BCS between the two groups at 8, 12 and 24 h. The incidence of postoperative adverse reactions was significantly lower in the combination analgesia group than that in the intravenous analgesia group (P<0.05). Conclusion Ultrasound guided TAP block combined with intravenous injection of parecoxib sodium for analgesia after laparoscopic myomectomy is effective, with low incidence of adverse reactions. Key words: Transversus abdominis plane block; Ultrasonography; Parecoxib sodium; Pain, postoperative; Analgesia, patient-controlled; Uterine perforation; Laparoscopes