Abstract

Summary 1 Following stress there may be an increased utilization of pantothenic acid in the production of acetylcholine. Relative deficiencies of pantothenic acid could result in intestinal atony under such circumstances. 2 A significant period of adynamic ileus was readily produced in dogs by a combination of exposure and manipulative trauma to the gut and peritoneum. 3 The duration of ileus produced by this method was significantly reduced in 21 dogs by the administration of d -pantothenyl alcohol. 4 These findings suggest that d -pantothenyl alcohol may prove to be of use in paralytic ileus following surgery.

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