Abstract
Adult male rats exposed to alcohol in utero results in reduction of the volume of the sexually dimorphic nucleus of the preoptic area (SND-POA). Reduction of the volume of this nucleus is also significantly reduced in rats exposed to ethanol postnatally compared to the volume in animals not exposed to ethanol ( P < 0.05). The results indicate that ethanol exposure during the postnatal period of brain development in rats is equally effective as in utero ethanol exposure in development of the SDN-POA volume. This report substantiates others demonstrating the deleterious effects of ethanol consumption during the ‘critical’ period of brain development.
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