Abstract
Objective To identify the real number of hyperhomocysteinemic Alzheimer's patients who may benefit from homocysteine-lowering therapy. Methods Basal and post-methionine load homocysteine levels were assessed by rp-HPLC system. Results PML test revealed twice as many hyperhomocysteinemic AD subjects with respect to the fasting analysis. Conclusion PML test resulted useful in detecting higher number of hyperhomocysteinemic AD patients who may have the chance of an early folate treatment.
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