Abstract
Positron emission tomography (PET) imaging has increased substantially in recent years. PET allows noninvasive evaluation of myocardial blood flow, function, and metabolism. The advantages of cardiac PET imaging over SPECT are [1]: improved image quality (especially in obese patients) with high both temporal and spatial resolution, relatively short imaging protocols, routine attenuation correction (depth independent), providing peak stress ejection fraction (EF)-no time delay between hyperemic response and imaging and true quantification of myocardial blood flow and myocardial metabolism. In addition, PET provides equal sensitivity with higher specificity and diagnostic accuracy compared to SPECT. However, cardiac PET still faces the challenges of being less available, with a greater cost, less expertise, challenges of performing exercise stress due to the short half-life of the currently available radiotracers making pharmacological stress testing the only current option (until the availability of new radiopharmaceutical agents), and reimbursement issues.
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