Abstract

Despite guideline-directed disease-modifying therapies, patients suffering from heart failure with reduced ejection fraction (HFrEF) continue to face long-term clinical sequelae. Empagliflozin, a sodium glucose co-transporter 2 inhibitor (SGLT2i), has been shown to reduce hospitalizations and deaths in patients with HFrEF. We conducted a cost-utility analysis to estimate the value of add-on empagliflozin versus usual care (UC) for HFrEF from a UK healthcare system perspective.

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