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https://doi.org/10.1016/j.bmcl.2004.04.044
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Cite Publication Date: May 7, 2004 | |
 Citations: 23 |
Affiliation: Wuhan University, Peking University, Lanzhou University
Three new porphyrin–DNA cross-linking conjugates 8, 9, and 10 have been synthesized. Their photoinduced DNA cleavage activity have been studied. The IC 50 values to THP-1 cells in the presence of porphyrin derivatives 8, 9, and 10 with photoirradiation were 5.6, 88.4, and 61.8 nM, respectively.
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