Abstract
Eccrine poromas are rare, benign adnexal tumors derived from the intraepidermal portion of sweat ducts. Historically they were thought to arise from eccrine ducts although today it is thought that they may also have an apocrine origin. They usually appear as solitary, slow-growing, skin-colored papules on acral surfaces. Here we present the unusual situation of a patient with multiple poromas who was previously treated with chemotherapy and radiation for Ewing sarcoma. This report adds to the increasing evidence that connect multiple poromas to some treatments of malignant conditions.
Highlights
A poroma is a benign adnexal neoplasm composed of epithelial cells that show tubular differentiation, whereas a porocarcinoma is a malignant poroma which can cause visceral metastasis [1]
Multiple poromas or eccrine poromatosis is an uncommon phenomenon and more than half of the reported cases had a history of immunosuppression from either radiation or chemotherapy [3]
Eccrine poroma (EP) is a benign, mostly asymptomatic, slow growing or stable neoplasm appearing as nodular lesions, occasionally pigmented, which occurs typically on the palms and soles [4]
Summary
Amr Abduljabbar1*, Omar Alanazi, Amany Fathadin and Mohammad Alhaddab2 1Department of Dermatology, King Saud Medical City, Riyadh, Saudi Arabia 2Department of Dermatology, King Saud University Hospital, Riyadh, Saudi Arabia 3Department of Pathology, King Saud University Hospital, Riyadh, Saudi Arabia
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