Porokeratotic Eccrine Ostial and Dermal Duct Nevus

Mona Masoumeh Naraghi,Azadeh Goodarzi,Azita Nikoo

doi:10.1155/2013/953840

Abstract

PEODDN is a rare benign cutaneous disorder that clinically resembles comedo nevus but favors the palms and soles, where pilosebaceous follicles are absent. Widespread involvement along Blaschko's lines can also occur. It is a disorder of keratinization involving the intraepidermal eccrine duct (acrosyringium) and is characterized by eccrine hamartoma and cornoid lamellation in pathology. The patient is a 29-year-old man with an 8-year history of pruritic skin lesions on his right lateral ankle. In the pathologic examination, multiple small epidermal invagination with overlying parakeratotic cornoid lamellation, loss of granular layer, and few dyskeratotic cells at the base of epidermal invagination are revealed. After clinic-pathologic correlation, the diagnosis of porokeratotic eccrine ostial and dermal duct nevus (PEODDN) was made. Late-onset and rare clinical presentation as pruritic lesion are the characteristic features that make this patient an extraordinary presentation of PEODDN.

Highlights

The term Porokeratotic Eccrine Ostial and Dermal Duct Nevus (PEODDN) was first described in 1980 by Abell and Read [1]
PEODDN is a very rare skin condition which is classified as porokeratotic dermatoses
A 29-year-old Iranian gentleman was referred to the Dermatology Department of RAZI Skin Hospital with severe pruritic skin lesions on his right lateral ankle that had presented since 8 years ago

Summary

Introduction

The term Porokeratotic Eccrine Ostial and Dermal Duct Nevus (PEODDN) was first described in 1980 by Abell and Read [1]. It was first described by Marsden et al in 1979 [2]. PEODDN is a very rare skin condition which is classified as porokeratotic dermatoses It is characterized by cornoid lamella which is a column of parakeratotic cells and is associated with dyskeratosis in the spinous layer as well as reduction in the number of granular zone cells. It is in close association with subjacent acrosyringia [3].

Case Report

Discussion