Abstract
We consider populations of RNA molecules as computational model for molecular evolution. Based on a large body of previous work, we review some recent results. In the first place, we study the sequence–structure map, its implications on the structural repertoire of a pool of random RNA sequences and its relevance for the RNA world hypothesis of the origin of life. In a scenario where template replication is possible, we discuss the internal organization of evolving populations and its relationship with robustness and adaptability. Finally, we explore how the effect of the mutation rate on fitness changes depends on the degree of adaptation of an RNA population.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
