Population dataset for 21 simple tandem repeat loci in the Akan population of Ghana.

Abd Rashid Nur Haslindawaty,Mohd Yusmaidie Aziz,Geoffrey Keith Chambers,Shaharum Shamsuddin,Hisham Atan Edinur,Anita Ghansah,Hashom Mohd Hakim,Abban Edward Kofi,Siti Afifah Ismail,Hussein Omar Khan

doi:10.1016/j.dib.2020.105746

Abstract

Short tandem repeat (STR) loci are widely used as genetic marker for ancestral and forensic analyses. The latter application includes for paternity testing and DNA profiling of samples collected from scenes of crime and suspects. This survey provides the first dataset for 21 STR loci across the Akan population in Ghana by genotyping of 109 unrelated healthy individuals using Investigator 24plex kit. None of the STR loci screened deviated from Hardy-Weinberg equilibrium after applying Bonferroni correction. Overall, 224 unique alleles were observed with allele frequencies ranging from 0.005 to 0.518. The combined match probability, combined power of exclusion and combined power discrimination were 1 in 4.07 × 10−25, 0.999999999 and 1, respectively. Principal coordinate analysis carried out using 21 STR allele frequency data mapped the Akans with Nigerian subpopulation groups (Hausa, Igbo and Yoruba), but separated from Thais of Thailand, Chechen of Jordan and Tijuana of Mexico.

Highlights

Short tandem repeat (STR) loci are widely used as genetic marker for ancestral and forensic analyses
The latter application includes for paternity testing and DNA profiling of samples collected from scenes of crime and suspects. This survey provides the first dataset for 21 STR loci across the Akan population in Ghana by genotyping of 109 unrelated healthy individuals using Investigator 24plex kit
None of the STR loci screened deviated from Hardy-Weinberg equilibrium after applying Bonferroni correction

Summary

Data accessibility

Genetics DNA profiling Tables and figure Capillary electrophoresis of STR polymerase chain reaction amplified products on 3500XL Genetic Analyser (Applied Biosystems, USA) Raw and analyzed Genomic DNA samples extracted from cheek cells were used as templates for amplification of 21 STR loci using Investigator 24plex QS kits (Qiagen, Germany) Comparison of separated STR fragments with standard allelic ladder included in the Investigator 24plex QS kit using the GeneMapper IDx v4.1 software (Applied Biosystems, USA).

Data description

Ethical clearance

Sample collection

DNA isolation and STR amplification

Findings

Statistical analysis